Program (preliminary)

SATURDAY JULY 26, 2008 · 8:30am–5:30pm · PLAZA BALLROOM · HYATT REGENCY · CHICAGO, USA

MORNING SESSION

09:00 a.m. - 09:15 a.m.

Introduction – Jeffrey Noebels, MD, PhD (Baylor College of Medicine)

09:15 a.m. - 09:45 a.m.

Evidence for Epilepsy in AD Models and Relation to Cognitive Impairments – Lennart Mucke, MD (Gladstone Institutes and UCSF)

09:45 a.m. - 10:15 a.m.

Effects of Aβ on Synaptic Functions – Roberto Malinow, PhD (Cold Spring Harbor Laboratory)

10:15 a.m. - 10:45 a.m. Role of Endogenous Synaptic Activity and Endocytosis in Aβ Release in Vivo – David Holtzman, MD (Washington University School of Medicine)
10:45 a.m. - 11:15 a.m. Break
11:15 a.m. - 11:45 a.m. Role of BACE1 in the Regulation of Sodium Channel Activity – Dora Kovacs, PhD (Massachusetts General Institute for Neurodegenerative Disease and Harvard Medical School)
11:45 a.m. - 12:15 a.m.

Role of Sodium Channels in Epilepsy – Lori Isom, PhD (University of Michigan School of Medicine)

12:30 p.m. - 01:30 p.m. Lunch on your own

AFTERNOON SESSION

01:30 p.m. - 02:00 p.m.

Clinical Evidence for Epilepsy in AD – Allen Hauser, MD (Columbia University)

02:00 p.m. - 02:30 p.m.

Detecting Nonconvulsive Seizure Activity in Humans – Andrew Cole, MD (Massachusetts General Hospital and Harvard Medical School)

02:30 p.m. - 03:00 p.m.

Role of Neural System Remodeling in AD – Bradley Hyman, MD, PhD (Massachusetts General Hospital and Harvard Medical School)

03:00 p.m. - 03:30 p.m. Break
03:30 p.m. - 04:00 p.m.

Polygenic Aspects of AD and Epilepsy: Is there an Overlap? – Jeffrey Noebels, MD, PhD (Baylor College of Medicine)

04:00 p.m. - 04:30 p.m.

Pharmacological Aspects of AD and Epilepsy: Is there an Overlap? – Marc Dichter, MD, PhD (University of Pennsylvania)

04:30 p.m. - 05:30 p.m.

Roundtable Discussion: Role of Epilepsy in AD Pathogenesis and Therapeutic Implications

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